Metromaf-250

Metromaf

COMPOSITION:

Each film coated tablet of Metromaf contains:

Metronidazole ………………….…………….. 250mg

DESCRIPTION:

Metronidazole is a nitroimidazole compound that acts on anaerobic microbes by depleting them of reducing equivalents and by disrupting the structure of their DNA. It is well absorbed orally and widely distributed throughout the body.

INDICATION:

Metronidazole is indicated for the treatment of confirmed trichomoniasis caused by Trichomonas vaginalis (except for in the first trimester of pregnancy) and the patient’s sexual partners, bacterial vaginosis, certain types of amebiasis, and various anaerobic infections. The above anaerobic infections may occur on the skin and skin structures, the abdomen, the heart, reproductive organs, central nervous system, and the respiratory system. Some may also be present in the bloodstream in cases of septicemia. Common infections treated by metronidazole are Bacteroides species infections, Clostridium infections, and Fusobacterium infections, as well as Peptococcus and Peptostreptococcus infections. Topical formulations of metronidazole are indicated for the treatment of inflammatory lesions of rosacea.

It is also used off-label in the treatment of Crohn’s disease, as a prophylactic agent after surgery5, and in the treatment of Helicobacter pylori infection.7 It has also been studied in the prevention of preterm births and to treat periodontal disease

DOSAGE:

For amebiasis:

Adults: For acute intestinal amebiasis: 750 milligrams (mg) 3 times a day for 5 to 10 days.

For amebic liver abscess: 500 to 750 mg 3 times a day for 5 to 10 days.

Children: Dose is based on body weight and must be determined by your doctor. The dose is usually 35 to 50 milligrams per kilogram of body weight (mg/kg) per day, divided into 3 doses, for 10 days.

For bacterial infections:

Adults: Dose is based on body weight and must be determined by your doctor. The dose is usually 7.5 milligrams per kilogram of body weight (mg/kg) every 6 hours for 7 to 10 days. Your doctor may increase your dose as needed. However, the dose is usually not more than 4 grams (g) per day.

Children: Use and dose must be determined by your doctor.

For trichomoniasis infections:

Adults:

One-day treatment: 2 grams (g) given as a single dose or 1 g given in 2 doses per day.

7-day course treatment: 250 mg 3 times a day for 7 days.

Children: Use and dose must be determined by your doctor.

Storage Conditions:

– Keep the medicine in a dry place at a temperature below 30 °C.

– Keep the medicine out of the reach of children.

– Protect the medicine from direct sunlight.

– Do not use Metromaf after expire date.